Check that Serato Sample and host DAW are up to date. You can check the build of Sample you're running by opening up settings within the plugin, the build number will be in the bottom right-hand corner, the latest build for Sample can be found here:
Remove all Plugins (1 by 1)
If the crash occurs with multiple versions of Serato Sample, try removing the Sample plugin from the session, this will determine if Sample is contributing to or causing the crash you're facing.
If the DAW continues to crash after removing Sample, remove each other plugin from the session 1 at a time to track down the offending plugin.
If the DAW doesn't crash after only removing Serato Sample, add Sample back to the session and swap out the audio file. Either for another, higher quality copy of the song or for a re-encoded version of the file you were previously using.
You can read more about here: https://support.serato.com/hc/en-us/articles/202310574-Re-encoding-corrupt-files-using-iTunes
Serato Sample generates & saves a report about the crash, forwarding this to the support team can help narrow down the cause of the crashing in some circumstances.
This report can be found; /userlibrary/application support/serato/sample/reports
Please note: The User Library may be hidden on OSX 10.7 and later versions. To show the User Library, click on the desktop and select “GO” from the Menu Bar at the top of the screen. While the GO menu is open, hold the Option (Alt) key on your keyboard and you will see a “Library” option appear in the list. This is how to access the hidden User Library folder, you are then able to navigate to the location listed above.
If you find Sample is still crashing after following all troubleshooting please submit a help request with the support team here
Further DAW specific troubleshooting can be found within the host DAWs knowledge base.
Ableton Live troubleshooting: https://help.ableton.com/hc/en-us/articles/209773265-Troubleshooting-crashes-of-Live
FL Studio troubleshooting: https://support.image-line.com/knowledgebase/base.php?ans=22
Logic Pro troubleshooting: https://support.apple.com/en-us/HT200260