Some users have reported problems with Serato software running on machines with AMD processors. Our in-house testing has also shown that AMD equipped PCs can, in some cases cause serious performance problems.

We do support use of Serato DJ with computers running AMD processors however if you are having constant performance issues please consider checking if your computer is meeting the minimum system requirements.
  
Workarounds

• Try all available USB ports
• Make sure other processes are not running in the background
• Ensure you're not using a USB hub or splitter
• Try plugging in an external drive (or memory stick) into another USB port on your machine - preferably the adjacent port. This may stimulate the machine’s chipset so that your problem may be fixed. If this does not help, please create a Help Request with the Support Team and describe your problem to help us investigate this issue further.

NOTE: Most of these issues do not appear to affect modern AMD CPU series, such as Ryzen.