Distorted audio when using 'i' series MacBook Pro computers with Rane MP 4

We have discovered an issue with the new 'i' series processor MacBook Pros (i5 and i7 processors) when used with the Rane MP 4. The problem is best described as distorted audio.

This is caused by a fundamental change to the internal USB hub in this series of Macbook Pro computers. Apple are aware of this problem and will be providing a fix in a future system update.